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Student Profiles:
jbonomo

Jason Bonomo, PhD



Matriculated: 2009

Graduate Program: Molecular Medicine & Translation Science

Education:

BA, Anthropology, Biology (with Honors), cum laude
Case Western Reserve University, 2009

PhD, Molecular Medicine & Translational Science
Wake Forest University, 2014

Research:
Genetic determinants of type 2 diabetes associated end-stage kidney disease and related phenotypes in African and European Americans.

Presentations:
Associations Between the Reticulon 1 Gene (RTN1) and End-Stage Kidney Disease. American Society of Nephrology, Annual Meeting. San Diego, CA. November 2015.

The ras responsive transcription factor RREB1 is a novel candidate gene for type 2 diabetes associated end-stage kidney disease. American Society of Nephrology Annual Conference, November 2013. Atlanta, GA.

Coding variants in nephrin (NPHS1) are associated with susceptibility to end-stage renal disease in African Americans. American Society of Nephrology Annual Conference, November 2013. Atlanta, GA.

Publications:
Yeo NC, O'Meara CC, Bonomo JA, Veth KN, Tomar R, Flister MJ, Drummond IA, Bowden DW, Freedman BI, Lazar J, Link BA, Jacob HJ. Shroom3 contributes to the maintenance of the glomerular filtration barrier integrity. Genome Res. 2015 Jan;25(1):57-65.

Bonomo JA, Guan M, Ng MC, Palmer ND, Hicks PJ, Keaton JM, Lea JP, Langefeld CD, Freedman BI, Bowden DW. The ras responsive transcription factor RREB1 is a novel candidate gene for type 2 diabetes associated end-stage kidney disease. Hum Mol Genet. 2014 Dec 15;23(24):6441-7.

Bonomo JA, Ng MC, Palmer ND, Keaton JM, Larsen CP, Hicks PJ; T2D-GENES Consortium, Langefeld CD, Freedman BI, Bowden DW. Coding variants in nephrin (NPHS1) and susceptibility to nephropathy in African Americans. Clin J Am Soc Nephrol. 2014 Aug 7;9(8):1434-40.

Bonomo Jason A, Palmer ND, Hicks PJ, Lea JP, Okusa MD, Langefeld CD, Bowden DW, Freedman BI. Complement factor H gene associations with end-stage kidney disease in African Americans. 2014. Nephrol Dial Transplant. http://www.ncbi.nlm.nih.gov/pubmed/24586071

Cooke Bailey JN, Palmer ND, Ng MC, Bonomo JA, et al. Analysis of coding variants identified from exome sequencing resources for association with diabetic and non-diabetic nephropathy in African Americans. 2014. Hum Genet. http://www.ncbi.nlm.nih.gov/pubmed/24385048

Ryan SO, Bonomo Jason A, Zhao F, Cobb BA. MHCII glycosylation modulates Bacteroides fragilis carbohydrate antigen presentation. The Journal of Experimental Medicine. 2011 May; 208(5):1041-1053. http://www.ncbi.nlm.nih.gov/pubmed/21502329

Honors and Awards:
Ruth L. Kirschstein National Research Service Award, 2013-present
National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health
Grant Number: F30 DK098836
Grant Title: “Detecting of coding variants modulating diabetic nephropathy in African Americans.”
-Multiyear training grant awarded by the NIDDK/NIH to fund my graduate and medical education, support my research endeavors, and aid in professional development.
http://projectreporter.nih.gov/project_info_description.cfm?aid=8522612&icde=19556142

Cultural Awareness Award, Wake Forest School of Medicine, 2014

MD/PhD Program Scholarship. 2009-present.

Professional Society Memberships:
American Society of Nephrology
American Medical Association

Interests & Hobbies:
Traveling, backpacking, camping, tennis, running, kayaking, concerts, photography, painting.

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